Li Yan Selected Research

Triple Negative Breast Neoplasms

11/2022	Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer.
5/2021	A Novel Three-Gene Score as a Predictive Biomarker for Pathologically Complete Response after Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer.
1/2021	Cytotoxic T-lymphocyte infiltration and chemokine predict long-term patient survival independently of tumor mutational burden in triple-negative breast cancer.
1/2021	Low expression of miR-195 is associated with cell proliferation, glycolysis and poor survival in estrogen receptor (ER)-positive but not in triple negative breast cancer.
10/2020	Abundance of Regulatory T Cell (Treg) as a Predictive Biomarker for Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer.
9/2020	ITPKC as a Prognostic and Predictive Biomarker of Neoadjuvant Chemotherapy for Triple Negative Breast Cancer.
9/2020	CD8 T Cell Score as a Prognostic Biomarker for Triple Negative Breast Cancer.
1/2020	Regulation of hypoxia-inducible factor functions in the nucleus by sphingosine-1-phosphate.
12/2019	High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer.
8/2019	Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammation, and Angiogenesis.

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Li Yan Research Topics

Disease

233	Neoplasms (Cancer) 05/2024 - 12/2002
73	Breast Neoplasms (Breast Cancer) 10/2023 - 11/2003
45	Inflammation (Inflammations) 04/2024 - 04/2006
44	Neoplasm Metastasis (Metastasis) 12/2023 - 11/2003
37	Type 2 Diabetes Mellitus (MODY) 10/2023 - 09/2005
28	Infections 02/2024 - 10/2009
27	Insulin Resistance 02/2024 - 04/2006
26	Wounds and Injuries (Trauma) 03/2024 - 11/2009
25	Obesity 04/2024 - 01/2013
24	Colorectal Neoplasms (Colorectal Cancer) 12/2024 - 03/2005
23	Hypertension (High Blood Pressure) 02/2024 - 07/2007
23	Ischemia 01/2024 - 08/2005
18	Lung Neoplasms (Lung Cancer) 02/2024 - 01/2013
17	Ulcer 01/2021 - 05/2007
16	Body Weight (Weight, Body) 09/2022 - 01/2004
16	Diabetic Foot 12/2021 - 06/2013
15	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 03/2014
14	Fibrosis (Cirrhosis) 07/2023 - 07/2009
14	Heart Failure 04/2023 - 12/2005
14	Atherosclerosis 01/2023 - 05/2007
13	Ovarian Neoplasms (Ovarian Cancer) 05/2024 - 01/2010
13	Reperfusion Injury 11/2021 - 08/2005
12	Prediabetic State (Prediabetes) 03/2023 - 03/2014
12	Triple Negative Breast Neoplasms 11/2022 - 12/2013
12	Stomach Neoplasms (Stomach Cancer) 10/2022 - 12/2006
12	Liver Cirrhosis (Hepatic Cirrhosis) 08/2022 - 11/2007
12	Hyperglycemia 01/2022 - 05/2007
12	Pain (Aches) 01/2022 - 09/2013
12	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 01/2009
11	Pleural Effusion (Pleural Effusions) 04/2024 - 02/2015
11	Squamous Cell Carcinoma of Head and Neck 02/2024 - 06/2009
11	Stroke (Strokes) 01/2024 - 01/2017
11	Hemorrhage 01/2024 - 12/2016
11	Disease Progression 01/2024 - 06/2003
11	Albuminuria 01/2023 - 01/2014
10	COVID-19 01/2024 - 10/2020
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 05/2008
10	Carcinogenesis 12/2023 - 01/2010
10	Diabetes Mellitus 09/2023 - 11/2004
10	Osteoarthritis 01/2023 - 12/2014
10	Chronic Renal Insufficiency 01/2023 - 11/2015
10	Edema (Dropsy) 06/2022 - 02/2014
9	Hypoxia (Hypoxemia) 04/2024 - 12/2006
9	Carcinoma (Carcinomatosis) 11/2023 - 12/2006
9	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2005
9	Alzheimer Disease (Alzheimer's Disease) 06/2022 - 02/2013
9	Dyslipidemias (Dyslipidemia) 01/2022 - 09/2013
9	Keloid 01/2020 - 07/2005
8	Malignant Pleural Effusion 01/2024 - 02/2015

Drug/Important Bio-Agent (IBA)

80	Proteins (Proteins, Gene)FDA Link 01/2024 - 04/2005
67	Biomarkers (Surrogate Marker)IBA 04/2024 - 10/2005
51	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 09/2006
36	MicroRNAs (MicroRNA)IBA 10/2023 - 01/2012
32	Messenger RNA (mRNA)IBA 10/2023 - 03/2005
27	AlbuminsIBA 01/2024 - 01/2013
26	LipidsIBA 04/2024 - 05/2007
21	Insulin (Novolin)FDA Link 01/2023 - 09/2006
20	Blood Glucose (Blood Sugar)IBA 04/2024 - 09/2005
20	CytokinesIBA 02/2024 - 04/2006
20	AutoantibodiesIBA 01/2023 - 12/2005
19	EnzymesIBA 10/2023 - 08/2005
18	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 07/2005
17	RNA (Ribonucleic Acid)IBA 02/2024 - 04/2005
17	Therapeutic UsesIBA 01/2024 - 07/2008
17	Matrix Metalloproteinases (MMPs)IBA 01/2024 - 11/2003
17	Triglycerides (Triacylglycerol)IBA 01/2023 - 07/2007
17	Small Interfering RNA (siRNA)IBA 06/2022 - 04/2006
16	AntigensIBA 11/2023 - 11/2002
16	Estrogen ReceptorsIBA 01/2023 - 01/2014
15	CreatinineIBA 01/2023 - 07/2007
14	Anti-Bacterial Agents (Antibiotics)IBA 02/2024 - 06/2003
14	Transcription Factors (Transcription Factor)IBA 01/2023 - 10/2013
13	oxidized low density lipoproteinIBA 01/2022 - 07/2007
11	CholesterolIBA 02/2024 - 07/2007
11	InterferonsIBA 12/2023 - 04/2014
10	Interleukin-6 (Interleukin 6)IBA 04/2024 - 02/2012
10	Immune Checkpoint InhibitorsIBA 03/2024 - 08/2016
10	Monoclonal AntibodiesIBA 01/2024 - 01/2009
10	CollagenIBA 01/2023 - 07/2009
10	Indicators and Reagents (Reagents)IBA 01/2023 - 10/2007
10	Cisplatin (Platino)FDA LinkGeneric 12/2022 - 08/2014
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2022 - 04/2005
10	Phosphotransferases (Kinase)IBA 01/2022 - 04/2006
10	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2021 - 11/2003
10	AntibodiesIBA 01/2020 - 12/2002
9	HDL CholesterolIBA 01/2022 - 09/2012
9	MK 2206IBA 02/2015 - 04/2011
8	Adenosine Triphosphate (ATP)IBA 04/2024 - 07/2008
8	LigandsIBA 04/2024 - 01/2009
8	Evans Blue (Blue, Evans)FDA Link 01/2024 - 06/2015

Therapy/Procedure

108	Therapeutics 05/2024 - 10/2005
33	Drug Therapy (Chemotherapy) 01/2024 - 12/2006
14	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2024 - 03/2013
14	Neoadjuvant Therapy 05/2021 - 05/2019
13	Radiotherapy 01/2023 - 09/2013
11	Immunotherapy 12/2023 - 09/2014
11	Transplantation 10/2022 - 07/2008
9	Glycemic Control 10/2023 - 08/2011
9	Lasers (Laser) 01/2023 - 12/2006
8	Telescopes 11/2023 - 02/2019